Berberine Extract (Berberine HCL)

Berberine hydrochloride extract is a naturally occurring alkaloid compound found in various plants, especially the roots, stems, and bark from Berberidaceae, Ranunculaceae, and Rutaceae families such as Berberis vulgaris (Barberry), Coptis chinensis (Chinese Goldthread), Hydrastis canadensis (Goldenseal) and so on. These herbal have been used in traditional medicine for centuries in Chinese and Ayurvedic medicine for improving cognitive function, reducing inflammation, and regulating blood sugar levels. Now it has been studied and used in healthcare products, medicine, food, cosmetics, veterinary medicine, agriculture and other industries.

Extraction process of berberine hydrochloride:

The traditional extraction methods of berberine mainly include acid water/alkali water extraction, ethanol extraction, two-phase extraction, supercritical fluid extraction, etc. The main process includes:

Plant material collection: Prepared the dried roots, rhizomes, and bark of the barberry plant.

Solvent extraction: Extracted with organic solvents, such as methanol or ethanol to obtain a crude extract containing berberine and other compounds.

Purification: The crude extract undergoes various purification techniques, such as column chromatography or recrystallization to isolate berberine from other components.

Salt formation: The isolated berberine is then converted into its hydrochloride salt form (berberine hydrochloride) by reacting it with hydrochloric acid, which increases its stability and solubility.